Basic Information
VIS ID
TVIS10012644
Fusion event
HBV-LOC101928849 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
X protein|
Start
1648
Orient
-
Integrated sequence
CCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCACCAAATATTGCCCAAG| |GTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGG
Host Sequence
Chromosome
chr9
Cytoband
q33.1
Reference genome
GRCh37/hg19
Start
121713032/118950754 (Hg38)
End
121713032/118950754 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC101928849
Nearest miRNA
hsa-let-7a-1/Upstream/4741225; hsa-mir-12126/Downstream/1294225;
Nearest TSS
ENST00000422679/Upstream/210191; ENST00000565320/Downstream/258132;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/1205390, chr9-CpG: 97/Downstream/418054
Nearby gene
TLR4(-1233263) ; BRINP1(+215876) ;
Upstream sequence
tcaacaagacagaaagttaacaaggatatccaggaattgacagaaactttctgtcaacgagacagaaagttaataaggatatccaggaattgaactcagc
Downstream sequence
aggctcatgttatgtgtgctcctttttaatgaataaaTTACTAAGAATGTATATTCAATCACTGTAGTCTTAAAATCCCGGTTCTACAATTTAGTAAATT
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate