Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10012666
Fusion event
HBV-C8B integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|
Start
1806
Orient
-
Integrated sequence
ACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGC| |ACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGG
Host Sequence
Chromosome
chr1
Cytoband
p32.2
Reference genome
Start
End
57414849/56949176 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
Target gene
Nearest miRNA
hsa-mir-12136/Upstream/1723453; hsa-mir-101-1/Downstream/2784051;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/303612, chr1-CpG: 222/Downstream/473115
Upstream sequence
GAATATAGACACATTTGGGGCATGTCATTTCCAAAGGATCCATAtgctatatctggaatgtcccctccaaaactcatgttgaaatttaattgccattgta
Downstream sequence
acagttttgaaaggaggcacctttatgaggttattatgtcatgagggttctgccctcatgaatagattaatgctgttgtttcaggagagggttagttatc
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.