VISDB Viral Integration Site DataBase

VIS ID

TVIS10012673

Fusion event

HBV-C11orf49 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|

Start

1941

Orient

+

Integrated sequence

CATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTG| |GAGTTACTCTCGTTTTTGCCTTCTGACTTCTTTCCTTCAGTACGAGATCTTCTAGATACCGCCTCAGCTCTGTATCGGGAAGCCTTAGAGTCTCCTGAGC

Chromosome

chr11

Cytoband

p11.2

Reference genome

Start

End

47082919/47061368 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-1972 ; hsa-mir-3909 ; hsa-mir-4717-5p ; hsa-mir-6834-3p ; hsa-mir-6852-3p

Nearest miRNA

hsa-mir-129-2/Upstream/308176; hsa-let-7a-2/Downstream/118243;

Nearest TSS

Nearest CpG islands

None/Target, chr11-CpG: 30/Upstream/124526, chr11-CpG: 93/Downstream/115108

Upstream sequence

cctgcttttatagagcttacattctagGAATCAGGGAATTGCAGTGGGTCTATCTGAGTATGTGATAAAAATCTGTTAGTTTTTCTAAAATATCTATTGT

Downstream sequence

TTATGGTGGACAAAGTGATGTCAAGGGAAAATGCAGACACTTTAGGCTGAAATGAAGATGTTGGTCTGACTTCTTTTTGTAATTGCCTTGAACTTCACTT