Basic Information
VIS ID
TVIS10012675
Fusion event
HBV-chr12 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
X protein|
Start
1741
Orient
+
Integrated sequence
GCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAG| |TTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAAT
Host Sequence
Chromosome
chr12
Cytoband
p12.3
Reference genome
GRCh37/hg19
Start
16058295/15905361 (Hg38)
End
16058295/15905361 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-1244-3/Upstream/2989443; hsa-let-7i/Downstream/1767938;
Nearest TSS
ENST00000382841/Upstream/4462; ENST00000524480/Downstream/5811;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/22459, chr12-CpG: 54/Downstream/5785
Nearby gene
STRAP(-1885) ; DERA(+5891) ;
Upstream sequence
atggtgcgatctcagcttactgcaacctctgcctcccaggttcaagcgattctcctgcctcagcctcctgagtagctgggactacaggcatacaccacca
Downstream sequence
cgcccagctaatttttgtatttttagtagagacggggttttgccatgttggccaggatggtcttgatctcctgacctcgtgatccacccgcctcggcttc
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate