VISDB Viral Integration Site DataBase

VIS ID

TVIS10012683

Fusion event

HBV-MAP3K9 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|

Start

1253

Orient

-

Integrated sequence

TGCCCGGCAACGGCCAGGTCTGTGCCAAGTGTTTGCTGACGCAACCCCCACTGGCTGGGGCTTGGTCATGGGCCATCAGCGCATGCGTGGAACCTTTTCG| |GCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCCGCTTGTTTTGCTCGCAGCAGGTCTGGAGCAAACATTATCGGGACTGATAACTCTGTTGTCCTAT

Chromosome

chr14

Cytoband

q24.2

Reference genome

Start

End

71225511/70758794 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-34a-5p ; hsa-mir-339-5p ; hsa-mir-17-5p ; hsa-mir-188-5p ; hsa-mir-24-3p ; hsa-mir-218-5p ; hsa-mir-6734-5p ; hsa-mir-377-3p ; hsa-mir-19b-3p ; hsa-mir-19a-3p ; hsa-mir-190b ; hsa-mir-190a-5p ; hsa-mir-6738-5p ; hsa-mir-5194 ; hsa-mir-1914-3p ; hsa-mir-423-5p ; hsa-mir-3184-5p ; hsa-mir-199b-5p ; hsa-mir-199a-5p ; hsa-mir-1825 ; hsa-mir-455-5p ; hsa-mir-6783-5p ; hsa-mir-374a-3p ; hsa-mir-615-5p ; hsa-mir-5001-5p ; hsa-mir-762 ; hsa-mir-4498 ; hsa-mir-4492 ; hsa-mir-4430 ; hsa-mir-3652 ; hsa-mir-1287-5p ; hsa-mir-4696 ; hsa-mir-4695-3p ; hsa-mir-4518 ; hsa-mir-1266-5p ; hsa-mir-6798-5p ; hsa-mir-6732-5p ; hsa-mir-5094 ; hsa-mir-3158-3p ; hsa-mir-5088-5p ; hsa-mir-4446-3p ; hsa-mir-361-5p ; hsa-mir-152-3p ; hsa-mir-148b-3p ; hsa-mir-148a-3p ; hsa-mir-130a-3p ; hsa-mir-130b-3p ; hsa-mir-4295 ; hsa-mir-301a-3p ; hsa-mir-301b-3p ; hsa-mir-3666 ; hsa-mir-454-3p ; hsa-mir-6868-3p ; hsa-mir-4490 ; hsa-mir-651-3p ; hsa-mir-548b-3p ; hsa-mir-490-3p ; hsa-mir-3133 ; hsa-mir-205-5p ; hsa-mir-6738-3p ; hsa-mir-544a ; hsa-mir-767-5p ; hsa-mir-627-3p ; hsa-mir-4793-3p ; hsa-mir-3130-3p ; hsa-mir-216b-3p ; hsa-mir-205-3p ; hsa-mir-5003-3p ; hsa-mir-603 ; hsa-mir-8485 ; hsa-mir-3919 ; hsa-mir-125b-2-3p ; hsa-mir-3925-5p ; hsa-mir-4801 ; hsa-mir-4731-3p ; hsa-mir-4290 ; hsa-mir-371b-3p ; hsa-mir-8084 ; hsa-mir-519e-5p ; hsa-mir-515-5p ; hsa-mir-500a-5p ; hsa-mir-1273d ; hsa-mir-548ay-3p ; hsa-mir-548at-3p ; hsa-mir-548as-3p ; hsa-mir-548t-3p ; hsa-mir-548ap-3p ; hsa-mir-548aa ; hsa-mir-642a-5p ; hsa-mir-4469 ; hsa-mir-6758-3p ; hsa-mir-1248 ; hsa-mir-1237-3p ; hsa-mir-6769b-3p ; hsa-mir-4723-3p ; hsa-mir-3183 ; hsa-mir-2276-5p ; hsa-mir-6836-3p ; hsa-mir-6892-3p ; hsa-mir-640 ; hsa-mir-5001-3p ; hsa-mir-6781-3p ; hsa-mir-2682-3p ; hsa-mir-6829-3p ; hsa-mir-6791-3p ; hsa-mir-6778-3p ; hsa-mir-6754-3p ; hsa-mir-3934-5p ; hsa-mir-764 ; hsa-mir-3124-3p ; hsa-mir-384 ; hsa-mir-3685 ; hsa-mir-4693-5p ; hsa-mir-4742-3p ; hsa-mir-1183 ; hsa-mir-6771-5p ; hsa-mir-6799-5p ; hsa-mir-6851-5p ; hsa-mir-3689d ; hsa-mir-423-3p ; hsa-mir-6746-5p ; hsa-mir-15a-3p ; hsa-mir-1247-5p

Nearest miRNA

hsa-mir-208a/Upstream/3316864; hsa-mir-1185-1/Downstream/1758026;

Nearest TSS

Nearest CpG islands

None/Target, chr14-CpG: 35/Upstream/116179, chr14-CpG: 140/Downstream/49761

Upstream sequence

atccatacaatggaatattattaagccttaaaaaggaatgaaattctgagataagttacaacatggatgaatcttttttttttttttgagacggagtttc

Downstream sequence

actcgtttcccaggctggagtgcaatggcacaatcctggctcactgcaacctctgcctcctgggttcaagcgattctcctgcctcagtctcccgagtagc