VISDB Viral Integration Site DataBase

VIS ID

TVIS10012686

Fusion event

HBV-POMT2 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|

Start

2561

Orient

+

Integrated sequence

TGGACTCATAAGGTGGGGAACTTTACTGGGCTTTATTCTTCTACTGTACCTGTCTTTAATCCTCATTGGAAAACACCATCTTTTCCTAATATACATTTAC| |ACCAAGACATTATCAAAAAATGTGAACAGTTTGTAGGCCCACTCACAGTTAATGAGAAAAGAAGATTGCAATTGATTATGCCTGCCAGGTTTTATCCAAA

Chromosome

chr14

Cytoband

q24.3

Reference genome

Start

End

77742779/77276436 (Hg38)

Orient

-

Location type

UTR3

Target gene

miRNAs that regulate target gene

hsa-mir-146b-5p ; hsa-mir-542-3p ; hsa-mir-219b-3p ; hsa-mir-5190

Nearest miRNA

hsa-mir-1260a/Upstream/10146; hsa-mir-1185-1/Downstream/16671790;

Nearest TSS

Nearest CpG islands

None/Target, chr14-CpG: 35/Upstream/5007, chr14-CpG: 113/Downstream/43911

Upstream sequence

GCAGAGGAGGACTGCAGAAGTGACACTGGGAAAGCTCAGCAGGTGACAGGAACATTAGTCTGGAGAGGCCAGAGTCCCCACATCCCAGCACCACGCAGAT

Downstream sequence

TCCCTGCCCTGTCTCTCATCTACCTTGGGCGCTAAGCAAGGTTCCCATGGGCTCTCCCAGCAGCCAGGAGAATGCATCTGCCTTGCCCTCCAGGCCAGGC