VISDB Viral Integration Site DataBase

VIS ID

TVIS10012687

Fusion event

HBV-ETFA integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1741

Orient

+

Integrated sequence

GCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAG| |TTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAAT

Chromosome

chr15

Cytoband

q24.2

Reference genome

Start

End

76580910/76288569 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-92a-3p ; hsa-mir-25-3p ; hsa-mir-18a-5p ; hsa-let-7b-5p

Nearest miRNA

hsa-mir-10393/Upstream/526254; hsa-mir-11181/Downstream/2921219;

Nearest TSS

Nearest CpG islands

None/Target, chr15-CpG: 55/Upstream/96330, chr15-CpG: 51/Downstream/22653

Upstream sequence

gggaggctgaggatcacctgaggccaggagtttgagaccaatgtggccaacatggtgaaacaccatctctactaaaaatacaaaaaattagccggggatg

Downstream sequence

gtggtgtatgcctgtagtcccagctactcaggaggctgaggcatgagaatgagaattgcttgaacctgggaggcggaggttgcagtgagctgagatagta