VISDB Viral Integration Site DataBase

VIS ID

TVIS10012703

Fusion event

HBV-CBFA2T2 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|

Start

1314

Orient

-

Integrated sequence

TTGGTCATGGGCCATCAGCGCATGCGTGGAACCTTTTCGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCCGCTTGTTTTGCTCGCAGCAGGTCTG| |GAGCAAACATTATCGGGACTGATAACTCTGTTGTCCTATCCCGCAAATATACATCGTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGG

Chromosome

chr20

Cytoband

q11.22

Reference genome

Start

End

32162386/33574580 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-101-3p ; hsa-mir-106b-5p ; hsa-mir-92a-3p ; hsa-mir-7977 ; hsa-mir-7160-5p ; hsa-mir-5690 ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929 ; hsa-mir-510-5p ; hsa-mir-512-5p ; hsa-mir-1273g-3p ; hsa-mir-1910-3p ; hsa-mir-2467-3p ; hsa-mir-3202 ; hsa-mir-3714 ; hsa-mir-377-5p ; hsa-mir-4252 ; hsa-mir-4257 ; hsa-mir-4533 ; hsa-mir-455-3p ; hsa-mir-490-3p ; hsa-mir-5694 ; hsa-mir-605-3p ; hsa-mir-6086 ; hsa-mir-619-3p ; hsa-mir-6499-3p ; hsa-mir-6511a-5p ; hsa-mir-6516-5p ; hsa-mir-6807-5p

Nearest miRNA

hsa-mir-103a-2/Upstream/1336733; hsa-mir-1-1/Downstream/474539;

Nearest TSS

Nearest CpG islands

None/Target, chr20-CpG: 39/Upstream/83917, chr20-CpG: 17/Downstream/69784

Upstream sequence

caggcgtggtggcacatgcctgtaatcccagctactcgggtggctgaggcaggagaatggcttgaacccgggaggcagaggttgcagtgagccgagattg

Downstream sequence

tgccattgcactccagcctgggaaacgagtgaaactccatctcaaaaaaacaaacaaacaaaaaCTCTTATAAAAAGTTGTTTTCTTTTTAAGCAGGGAA