Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10012710
Fusion event
HBV-SLC2A2 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|
Start
1741
Orient
+
Integrated sequence
GCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAG| |TTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAAT
Host Sequence
Chromosome
chr3
Cytoband
q26.2
Reference genome
End
170738536/171020747 (Hg38)
Orient
-
Location type
Intronic
Target gene
Nearest miRNA
hsa-let-7g/Upstream/597585; hsa-mir-1224/Downstream/85917;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/111695, chr3-CpG: 20/Downstream/7536
Upstream sequence
AGATCTTTTAGTTCCAAAACATGTAAGCAAGTCaaggactgaggagctctgatccagacaatttgcacatgttactaatgaaaactctggacttgcagag
Downstream sequence
gtggtgtatgcctgtagtcccagctactcaggaggctgaggtgggaggattgcttgagcccaggaggttgctgctgcagtgagctatgattgcaccacca
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.