VISDB Viral Integration Site DataBase

VIS ID

TVIS10012713

Fusion event

HBV-LCORL integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|

Start

1974

Orient

+

Integrated sequence

CAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTTGCCTTCTGACTTCTTT| |CCTTCAGTACGAGATCTTCTAGATACCGCCTCAGCTCTGTATCGGGAAGCCTTAGAGTCTCCTGAGCATTGTTCACCTCACCATACTGCACTCAGGCAAG

Chromosome

chr4

Cytoband

p15.31

Reference genome

Start

End

17858990/17857367 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-155-5p ; hsa-mir-21-5p ; hsa-mir-6839-3p ; hsa-mir-4507 ; hsa-mir-3940-5p ; hsa-mir-1273e

Nearest miRNA

hsa-mir-12113/Upstream/4229410; hsa-mir-12115/Downstream/2670908;

Nearest TSS

Nearest CpG islands

None/Target, chr4-CpG: 46/Upstream/45763, chr4-CpG: 178/Downstream/163445

Upstream sequence

gaaatgacttaagactttgggggactgttgggaaggcatgattagttttgaaatgtgagcacaagagatttggaaggggtcaggggcagaatgatatagt

Downstream sequence

TGAAAAGAATCAATGAAAAGAACCAGGTAATAATTTTCTGGAGGCTATATATAGCTGGATATAATTGACCTTCTGACACATGGAGCATTTGGTAAAGTCC