VISDB Viral Integration Site DataBase

VIS ID

TVIS10012717

Fusion event

HBV-NDST1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1752

Orient

-

Integrated sequence

TACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGA| |GATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTT

Chromosome

chr5

Cytoband

q33.1

Reference genome

Start

End

149922805/150543243 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-191-5p ; hsa-mir-375 ; hsa-mir-296-3p ; hsa-mir-193b-3p ; hsa-mir-484 ; hsa-mir-331-3p ; hsa-mir-92a-3p ; hsa-let-7e-5p ; hsa-mir-24-3p ; hsa-mir-1277-5p ; hsa-mir-190a-3p ; hsa-mir-4789-5p ; hsa-mir-466 ; hsa-mir-4528 ; hsa-mir-5011-5p ; hsa-mir-4643 ; hsa-mir-4789-3p ; hsa-mir-410-3p ; hsa-mir-5706 ; hsa-mir-4782-5p ; hsa-mir-516b-5p ; hsa-mir-1299 ; hsa-mir-422a ; hsa-mir-378i ; hsa-mir-378h ; hsa-mir-378f ; hsa-mir-378e ; hsa-mir-378d ; hsa-mir-378c ; hsa-mir-378b ; hsa-mir-378a-3p ; hsa-mir-4638-3p ; hsa-mir-6756-3p ; hsa-mir-3127-3p ; hsa-mir-1972 ; hsa-mir-1306-5p ; hsa-mir-4690-5p ; hsa-mir-216a-3p ; hsa-mir-3681-3p ; hsa-mir-128-3p

Nearest miRNA

hsa-mir-10397/Upstream/810353; hsa-mir-103a-1/Downstream/978844;

Nearest TSS

Nearest CpG islands

None/Target, chr5-CpG: 87/Upstream/15118, chr5-CpG: 23/Downstream/81865

Upstream sequence

cccacacattaataatgggagactttaacaccccactgtcaacattagacagatcaacgagacagaaagtcaacaaggatacccaggaattgaactcagc

Downstream sequence

atcctgagtcttggggaggagaagggtttgcccagggtcccaAGGTCGGAAATCCAAATGTTCTGGCTCTCCTCACTGCGTGTGGCTGACTGTGAAGCAG