Basic Information
VIS ID
TVIS10012723
Fusion event
HBV-chr6 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|
Start
1687
Orient
-
Integrated sequence
TCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCA| |ACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTA
Host Sequence
Chromosome
chr6
Cytoband
q13
Reference genome
End
74580966/73871252 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
Nearest miRNA
hsa-mir-10398/Upstream/903499; hsa-mir-10524/Downstream/1557155;
Nearby gene
CD109(-42925) ; COL12A1(+1213076) ;
Upstream sequence
TGAACCTTCCATTCCATCTTGGATCATCTTCATTATTCTTTATTTTGAGTTTTTGCTACCCTTATCTAATTTCTTAATGTGTCTGTGCACTAACTCATAT
Downstream sequence
TAAATTTTATACTCCAACTTGTAGCCATTTAAGGATGAACAAAACTTACTATTTCACAATTAAGGACAAAACAGGAAAGTGGAAGTTACCATTCTTATCA
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate