VISDB Viral Integration Site DataBase

VIS ID

TVIS10012735

Fusion event

HBV-FAM135B integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|Polymerase|

Start

1575

Orient

-

Integrated sequence

TTGGGACTCTCTCGTCCCCTTCTCCGTCTGCCGTTCCGACCGACCACGGGGCGCACCTCTCTTTACGCGGACTCCCCGTCTGTGCCTTCTCATCTGCCGG| |ACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTC

Chromosome

chr8

Cytoband

q24.23

Reference genome

Start

End

139503932/138491689 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-6823-3p ; hsa-mir-2114-3p ; hsa-mir-615-3p ; hsa-mir-361-3p

Nearest miRNA

hsa-mir-1204/Upstream/3686744; hsa-mir-10400/Downstream/2240875;

Nearest TSS

Nearest CpG islands

None/Target, chr8-CpG: 109/Upstream/3033590, chr8-CpG: 119/Downstream/4863

Upstream sequence

tagccagaagcattctaagaaacatcttagggatgtttacattcaagtcacagagttgaacattccctttcacagagcacgtttgaaacaatcttctcgt

Downstream sequence

acagtgaactacgtaatatattgataagtactataaagaaagaaacatcaaaataagagactgtcattgtagaagtaggtggtaagggtgggctaatgat