SULF1 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10012740
Fusion event
HBV-SULF1 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
precore/core protein|Core and e antigen|
Start
2303
Orient
+
Integrated sequence
TGTGGTTTCACATTTCTTGTCTCACTTTTGGAAGAGAAACAGTTATAGAGTATTTGGTGTCTTTCGGAGTGTGGATTCGCACTCCTCCAGCTTATAGACC| |ACCAAATGCCCCTATCCTATCAACACTTCCGGAGACTACTGTTGTTAGACGACGAGGCAGGTCCCCTAGAAGAAGAACTCCCTCGCCTCGCAGACGAAGG
Host Sequence
Chromosome
chr8
Cytoband
q13.3
Reference genome
GRCh37/hg19
Start
70557401/69645166 (Hg38)
End
70557401/69645166 (Hg38)
Orient
-
Location type
Intronic
Target gene
SULF1
miRNAs that regulate target gene
hsa-mir-516a-3p ; hsa-mir-124-3p
Nearest miRNA
hsa-mir-124-1/Upstream/5265909; hsa-mir-10400/Downstream/4903377;
Nearest TSS
ENST00000518652/Upstream/6355; ENST00000533344/Downstream/68224;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/1313598, chr8-CpG: 224/Downstream/186697
Upstream sequence
aacttctttgtggtgtctgcattcaagtcacagaactgaacatcccctcacatagagcagttgtgcagcactctatttgtagtatctggaagtggacatt
Downstream sequence
GCCATGAGAGCTGGGTAGCGGCAGGGGTGACAACAGTGGCCACCCTGGTAAGGTTAAGGTCAGACTTGGGTTAGTCTAAGCTGTCAGAGGGTGTTCATCA
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate