VISDB Viral Integration Site DataBase

VIS ID

TVIS10012741

Fusion event

HBV-SLCO5A1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|Polymerase|

Start

2381

Orient

+

Integrated sequence

GCACTCCTCCAGCTTATAGACCACCAAATGCCCCTATCCTATCAACACTTCCGGAGACTACTGTTGTTAGACGACGAGGCAGGTCCCCTAGAAGAAGAAC| |TCCCTCGCCTCGCAGACGAAGGTCTCAATCGCCGCGTCGCAGAAGATCTCAATCTCGGGAATCTCAATGTTAGTATTCCTTGGACTCATAAGGTGGGGAA

Chromosome

chr8

Cytoband

q13.3

Reference genome

Start

End

70602345/69690110 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-192-3p ; hsa-mir-93-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-106a-5p ; hsa-mir-548t-5p ; hsa-mir-548az-5p ; hsa-mir-603 ; hsa-mir-8485 ; hsa-mir-4511 ; hsa-mir-548b-3p ; hsa-mir-548s ; hsa-mir-6873-3p ; hsa-mir-3926 ; hsa-mir-3190-5p ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-6892-3p ; hsa-mir-6849-3p ; hsa-mir-4801 ; hsa-mir-4731-3p ; hsa-mir-4684-5p ; hsa-mir-6769b-3p ; hsa-mir-4723-3p ; hsa-mir-3183 ; hsa-mir-1276 ; hsa-mir-320e ; hsa-mir-519a-3p ; hsa-mir-519b-3p ; hsa-mir-519c-3p ; hsa-mir-6128 ; hsa-mir-767-5p

Nearest miRNA

hsa-mir-124-1/Upstream/5310853; hsa-mir-10400/Downstream/4858433;

Nearest TSS

Nearest CpG islands

None/Target, chr8-CpG: 109/Upstream/1358542, chr8-CpG: 224/Downstream/141753

Upstream sequence

tagccagaagcattctaagaaacatcttagggatgtgtacattcaagtcacagagttgaacattcccctttctcagagcaggtttgaaacaatcttctcg

Downstream sequence

agactagagtcaagctcaacagggtcttctttccccgctgattccgccaagcccgttcccttggctgtggtttcgctggatagtaggtagggacagtggg