VISDB Viral Integration Site DataBase

VIS ID

TVIS10012744

Fusion event

HBV-TMEM245 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1741

Orient

+

Integrated sequence

GCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAG| |TTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAAT

Chromosome

chr9

Cytoband

q31.3

Reference genome

Start

End

111816474/109054194 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-374b-5p ; hsa-mir-340-5p ; hsa-mir-106b-5p ; hsa-mir-186-5p ; hsa-mir-221-3p ; hsa-mir-21-5p ; hsa-mir-16-5p ; hsa-mir-222-3p ; hsa-mir-183-5p ; hsa-mir-4662a-5p ; hsa-mir-3129-3p ; hsa-mir-5583-5p ; hsa-mir-93-3p ; hsa-mir-3692-5p ; hsa-mir-6507-5p ; hsa-mir-548a-3p ; hsa-mir-548e-3p ; hsa-mir-548f-3p ; hsa-mir-548ar-3p ; hsa-mir-5582-3p ; hsa-mir-548az-3p ; hsa-mir-374a-5p ; hsa-mir-20a-5p ; hsa-mir-526a ; hsa-mir-523-5p ; hsa-mir-522-5p ; hsa-mir-520c-5p ; hsa-mir-519c-5p ; hsa-mir-519b-5p ; hsa-mir-519a-5p ; hsa-mir-518f-5p ; hsa-mir-518e-5p ; hsa-mir-518d-5p ; hsa-mir-520g-5p ; hsa-mir-142-3p ; hsa-mir-4280 ; hsa-mir-562 ; hsa-mir-513c-3p ; hsa-mir-513a-3p ; hsa-mir-3606-3p ; hsa-mir-7844-5p ; hsa-mir-6864-3p ; hsa-mir-3672 ; hsa-mir-27b-5p ; hsa-mir-873-3p ; hsa-mir-376b-3p ; hsa-mir-376a-3p ; hsa-mir-3157-5p ; hsa-mir-95-3p ; hsa-mir-4524b-5p ; hsa-mir-4524a-5p ; hsa-mir-6801-5p ; hsa-mir-676-5p ; hsa-mir-103b ; hsa-mir-4691-3p ; hsa-mir-646 ; hsa-mir-503-5p ; hsa-mir-6838-5p ; hsa-mir-497-5p ; hsa-mir-424-5p ; hsa-mir-195-5p ; hsa-mir-15b-5p ; hsa-mir-15a-5p ; hsa-mir-205-3p ; hsa-mir-6513-5p ; hsa-mir-887-5p ; hsa-mir-3913-5p ; hsa-mir-3122 ; hsa-mir-450a-1-3p ; hsa-mir-5089-5p ; hsa-mir-6728-5p ; hsa-mir-769-3p ; hsa-mir-450b-3p ; hsa-mir-6844 ; hsa-mir-6071 ; hsa-mir-593-3p ; hsa-mir-193a-5p ; hsa-mir-5187-5p ; hsa-mir-5589-5p ; hsa-mir-4731-5p ; hsa-mir-187-5p ; hsa-mir-661 ; hsa-mir-4693-3p ; hsa-mir-9-5p ; hsa-mir-6728-3p ; hsa-mir-4686 ; hsa-mir-4712-3p ; hsa-mir-6512-5p ; hsa-mir-6793-3p ; hsa-mir-216b-3p ; hsa-mir-603 ; hsa-mir-8485 ; hsa-mir-4298 ; hsa-mir-1302 ; hsa-mir-3189-3p ; hsa-mir-212-5p ; hsa-mir-600 ; hsa-mir-502-5p ; hsa-mir-6798-3p ; hsa-mir-4640-3p ; hsa-mir-361-3p ; hsa-mir-519d-3p ; hsa-mir-93-5p ; hsa-mir-17-5p ; hsa-mir-20b-5p ; hsa-mir-1273f ; hsa-mir-129-5p ; hsa-mir-193b-5p ; hsa-mir-19a-5p ; hsa-mir-19b-1-5p ; hsa-mir-19b-2-5p ; hsa-mir-3170 ; hsa-mir-3665 ; hsa-mir-3674 ; hsa-mir-3680-3p ; hsa-mir-450b-5p ; hsa-mir-4732-5p ; hsa-mir-507 ; hsa-mir-557 ; hsa-mir-6511b-5p ; hsa-mir-6516-5p ; hsa-mir-657 ; hsa-mir-6811-5p ; hsa-mir-6832-5p ; hsa-mir-6855-5p ; hsa-mir-6890-5p

Nearest miRNA

hsa-let-7a-1/Upstream/7896; hsa-mir-12126/Downstream/457281;

Nearest TSS

Nearest CpG islands

None/Target, chr9-CpG: 64/Upstream/40540, chr9-CpG: 101/Downstream/65008

Upstream sequence

AAGTTGTTAGGAGTCAGGGCTGGGGTAGTCAGAACCATAGCTAAAACATTCTACCTGCTGAGAGATGCTACTAGTACTAATTATTCTTGTTATACAACaa

Downstream sequence

gtggtgtatgcctgtagtcccagctactcaggaggaagaaggaggaggatgaagcagaaggatggcttgagcccaggaggtcaaggatgcagtaagccac