ZNF114 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10012756
Fusion event
HBV-ZNF114 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|
Start
1774
Orient
-
Integrated sequence
CTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTA| |CTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTC
Host Sequence
Chromosome
chr19
Cytoband
q13.33
Reference genome
End
48778613/48275356 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-10395/Upstream/1048335; hsa-let-7e/Downstream/734550;
Upstream sequence
aagagagaggaagggagggagggagggagacagaAACATCCTAGGTTGGTCAGGCTTCGTGGctttaatcccagcactttgggaggctgaggcaggatga
Downstream sequence
tcgcctgaggtcaggagttcaagaccagcctggccaacatgatgaagtcctgtctctactaaaacacacacacacacacacacacacacacacacacaca
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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