Fusion event
HBV-ZNF114 integration
Detection method
PCR and Sanger sequencing
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Integrated sequence
CTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTA| |CTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTC
End
48778613/48275356 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-10395/Upstream/1048335; hsa-let-7e/Downstream/734550;
Upstream sequence
aagagagaggaagggagggagggagggagacagaAACATCCTAGGTTGGTCAGGCTTCGTGGctttaatcccagcactttgggaggctgaggcaggatga
Downstream sequence
tcgcctgaggtcaggagttcaagaccagcctggccaacatgatgaagtcctgtctctactaaaacacacacacacacacacacacacacacacacacaca
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.