VISDB Viral Integration Site DataBase

VIS ID

TVIS10012759

Fusion event

HBV-MYH14 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1722

Orient

-

Integrated sequence

TGAACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTT| |GTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAAC

Chromosome

chr19

Cytoband

q13.33

Reference genome

Start

End

50814110/50310853 (Hg38)

Orient

+

Location type

downstream

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-877-3p ; hsa-mir-615-3p ; hsa-mir-193b-3p ; hsa-mir-412-3p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-149-3p ; hsa-mir-4728-5p ; hsa-mir-8085 ; hsa-mir-6731-5p ; hsa-mir-6797-5p ; hsa-mir-1249-5p ; hsa-mir-4306 ; hsa-mir-4644 ; hsa-mir-185-5p ; hsa-mir-6133 ; hsa-mir-6130 ; hsa-mir-6129 ; hsa-mir-6127 ; hsa-mir-4510 ; hsa-mir-4419a ; hsa-mir-4756-5p ; hsa-mir-4739 ; hsa-mir-1321 ; hsa-mir-6873-5p ; hsa-mir-6760-5p ; hsa-mir-4428 ; hsa-mir-5196-5p ; hsa-mir-4747-5p ; hsa-mir-4533 ; hsa-mir-9500 ; hsa-mir-1275 ; hsa-mir-2467-3p ; hsa-mir-3127-5p ; hsa-mir-363-5p ; hsa-mir-4271 ; hsa-mir-4506 ; hsa-mir-4525 ; hsa-mir-4651 ; hsa-mir-4665-5p ; hsa-mir-4693-3p ; hsa-mir-4723-5p ; hsa-mir-4725-3p ; hsa-mir-5000-5p ; hsa-mir-5010-5p ; hsa-mir-5192 ; hsa-mir-5680 ; hsa-mir-5698 ; hsa-mir-608 ; hsa-mir-625-5p ; hsa-mir-6716-5p ; hsa-mir-6745 ; hsa-mir-6780b-5p ; hsa-mir-6782-5p ; hsa-mir-6798-5p ; hsa-mir-6870-5p ; hsa-mir-7111-5p ; hsa-mir-8071

Nearest miRNA

hsa-mir-10395/Upstream/377716; hsa-let-7e/Downstream/896076;

Nearest TSS

Nearest CpG islands

None/Target, chr19-CpG: 112/Upstream/1602, chr19-CpG: 23/Downstream/12670

Upstream sequence

atgagggaacagtctcagagcagcagcatccctcactccacgcccccagtgagtgctagaaggggtgttgcactcgggcCAACTCTTAAGTTTTGCAAAA

Downstream sequence

TAAATGACAGgcctgctgcagtggctcatacctgtgatcccagtgcttcgggaggctgaggtgggaggatcacttgagcccagggggtggaggctgcagt