KCNC2 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10012771
Fusion event
HBV-KCNC2 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
precore/core protein|Core and e antigen|
Start
1995
Orient
+
Integrated sequence
TTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTTGCCTTCTGACTTCTTTCCTTCAGTACGAGATCTTCTA| |GATACCGCCTCAGCTCTGTATCGGGAAGCCTTAGAGTCTCCTGAGCATTGTTCACCTCACCATACTGCACTCAGGCAAGCAATTCTTTGCTGGGGGGAAC
Host Sequence
Chromosome
chr12
Cytoband
q21.1
Reference genome
GRCh37/hg19
Start
75455539/75061759 (Hg38)
End
75455539/75061759 (Hg38)
Orient
-
Location type
Intronic
Target gene
KCNC2
Nearest miRNA
hsa-let-7i/Upstream/5476936; hsa-mir-1178/Downstream/4357498;
Nearest TSS
ENST00000382841/Upstream/10832; ENST00000548779/Downstream/78437;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/523660, chr12-CpG: 68/Downstream/145542
Upstream sequence
CATAGAGGTCATCACAAATATTCATAATTTTTATAGGGCTTAACAGTGAGTCCTAACGTCAAATATTCCTGAATGCTAATCCTAAAACTTTCTAATTTAT
Downstream sequence
AGACTTTTCTTACTCTTAACCAATCAGCAAGCCATCATAACTACATGATTTTTACAAATTGTTTTTAACTAATTCTATTCCCAAAAAGTAACTGTGTACC
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate