VISDB Viral Integration Site DataBase

VIS ID

TVIS10012773

Fusion event

HBV-TXNDC16 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|

Start

1101

Orient

-

Integrated sequence

GTGGGTCTTTTGGGTTTTGCTGCCCCTTTTACACAATGTGGTTATCCTGCGTTGATGCCTTTGTATGCATGTATTCAATCTAAGCAGGCTTTCACTTTCT| |CGCCAACTTACAAGGCCTTTCTGTGTAAACAATACCTGAACCTTTACCCCGTTGCCCGGCAACGGCCAGGTCTGTGCCAAGTGTTTGCTGACGCAACCCC

Chromosome

chr14

Cytoband

q22.1

Reference genome

Start

End

52966416/52499698 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-29c-3p ; hsa-mir-10b-5p ; hsa-mir-585-5p ; hsa-mir-4316 ; hsa-mir-4710 ; hsa-mir-4722-5p ; hsa-mir-6804-5p ; hsa-mir-125a-3p ; hsa-mir-6885-5p ; hsa-mir-552-3p ; hsa-mir-328-5p ; hsa-mir-486-3p ; hsa-mir-3622b-5p ; hsa-mir-1827 ; hsa-mir-4532 ; hsa-mir-4768-3p ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-5197-5p ; hsa-mir-6736-5p ; hsa-mir-4701-3p ; hsa-mir-1262 ; hsa-mir-7703 ; hsa-mir-6720-5p ; hsa-mir-6512-3p ; hsa-mir-661 ; hsa-mir-4252 ; hsa-mir-6776-5p ; hsa-mir-4793-3p ; hsa-mir-766-3p ; hsa-mir-6742-3p ; hsa-mir-6849-3p ; hsa-mir-1273g-3p ; hsa-mir-508-5p ; hsa-mir-3671 ; hsa-mir-372-5p ; hsa-mir-371a-5p ; hsa-mir-616-5p ; hsa-mir-373-5p ; hsa-mir-371b-5p ; hsa-mir-3163 ; hsa-mir-892c-3p ; hsa-mir-4676-3p ; hsa-mir-452-5p ; hsa-mir-429 ; hsa-mir-200c-3p ; hsa-mir-200b-3p ; hsa-mir-5692a ; hsa-mir-2909 ; hsa-mir-1296-5p ; hsa-mir-1258 ; hsa-mir-6781-5p ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-6499-5p ; hsa-mir-5693 ; hsa-mir-4512 ; hsa-mir-7160-3p ; hsa-mir-6895-5p ; hsa-mir-665 ; hsa-mir-6771-5p ; hsa-mir-7977 ; hsa-mir-566 ; hsa-mir-7160-5p ; hsa-mir-6720-3p ; hsa-mir-6499-3p ; hsa-mir-6884-5p ; hsa-mir-485-5p ; hsa-mir-4537 ; hsa-mir-20b-3p ; hsa-mir-17-3p ; hsa-mir-4649-3p ; hsa-mir-6746-5p ; hsa-mir-5690 ; hsa-mir-2114-5p ; hsa-mir-5588-3p ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929 ; hsa-mir-596 ; hsa-mir-125b-2-3p ; hsa-mir-1273h-5p ; hsa-mir-149-3p ; hsa-mir-30b-3p ; hsa-mir-30c-1-3p ; hsa-mir-30c-2-3p ; hsa-mir-3122 ; hsa-mir-3689a-3p ; hsa-mir-3689b-3p ; hsa-mir-3689c ; hsa-mir-3913-5p ; hsa-mir-3974 ; hsa-mir-4433a-3p ; hsa-mir-4457 ; hsa-mir-4459 ; hsa-mir-450a-1-3p ; hsa-mir-4728-5p ; hsa-mir-4767 ; hsa-mir-513b-5p ; hsa-mir-6087 ; hsa-mir-6089 ; hsa-mir-624-3p ; hsa-mir-6513-5p ; hsa-mir-6779-5p ; hsa-mir-6780a-5p ; hsa-mir-6785-5p ; hsa-mir-6788-5p ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-7106-5p ; hsa-mir-887-5p

Nearest miRNA

hsa-mir-208a/Upstream/2199752; hsa-mir-1185-1/Downstream/1448729;

Nearest TSS

Nearest CpG islands

None/Target, chr14-CpG: 35/Upstream/184407, chr14-CpG: 126/Downstream/52622

Upstream sequence

tggccactatcaaaaaaaaaaaaagaaaagaaagaaaagaatgacaaacgttggtgaagatatgaagaaatgaacccttgtgcactgttggtgagactgt

Downstream sequence

aaaatggtgcaggcactatgaaaacagtacagtcatccctcagtatccataaggaatcagtttctctacaccccttaaatataccaaaatccataaatgt