Basic Information
VIS ID
TVIS10012776
Fusion event
HBV-ITFG1-AS1 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
Polymerase|large S protein|middle S protein|
Start
95
Orient
+
Integrated sequence
AATTCCACAACCTTCCACCAAACTCTGCAAGATCCCAGAGTGAGAGGCCTGTATTTCCCTGCTGGTGGCTCCAGTTCAGGAACAGTAAACCCTGT| |TCTGACTACTGCCTCTCCCTTATCGTCAATCTTCTCGAGGATTGGGGACCCTGCGCTGAACATGGAGAACATCACATCAGGATTCCTAGGACCCCTTCTC
Host Sequence
Chromosome
chr16
Cytoband
q12.1
Reference genome
End
47184799/47150888 (Hg38)
Orient
-
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-1225/Upstream/12987215; hsa-mir-11401/Downstream/3141728;
Nearby gene
NETO2(-6863) ; ITFG1(+4499) ;
Upstream sequence
ctaaaaacacaaaaattagccaggcatggtgtcacacacctgtagtcccagctacttgggaggctgaggcaggacaattgcttgaacctgggaggcagag
Downstream sequence
gctgcagtgagccgagatcacaccactgcactccagcctgggtgacagagcaagactccatctcaaaaaaaaaatttttttttctttgcatatatagctt
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate