Basic Information
VIS ID
TVIS10012807
Fusion event
HBV-LOC105374602 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
X protein|
Start
1756
Orient
-
Integrated sequence
TAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATT| |AGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATG
Host Sequence
Chromosome
chr5
Cytoband
p15.33
Reference genome
GRCh37/hg19
Start
26816/26816 (Hg38)
End
26816/26816 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC105374602
Nearest miRNA
hsa-mir-10397/Downstream/1036080;
Nearest TSS
ENST00000502646/Downstream/65335;
Nearest CpG islands
None/Target, None/Upstream, chr5-CpG: 87/Downstream/23874
Nearby gene
PLEKHG4B(+113557) ;
Upstream sequence
aaattgttctgaatttggtccatgggagcAATATAGAGATATGAAATTTGTCTCTTTACCATATTTCAGGGATTGTTTATGTTTTTCTAAAATAAAAAGt
Downstream sequence
acatgttatttcatcatccaggtattaagcccagtgcccgatagttatgtcttctgctcccctccctcctcccaccctcccccactcaagtagatcccag
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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