Fusion event
HBV-GTF2I integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Region type
X protein|precore/core protein|
Integrated sequence
AAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTT| |CACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAAT
End
74123332/74709001 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-10525/Upstream/112975; hsa-mir-10399/Downstream/1206196;
Upstream sequence
AACTCTTGTCCACACATTCCTTAATTAAAACAGAAATAAATGCACACCCATTAGAGTTCTTGTTTCTGCAGTGCTGTGGCTGAACTGGAGTGGGACCAGG
Downstream sequence
TTACCTGCTCTTTAAATGCAGTGCAAACCTATTTGAGTAATCTCTAGTCTAATGGACAAATGGAAAGGAAACTTCCAGCCAAACTATTGTGAAATACTAC
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.