Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10012830
Fusion event
HBV-AGBL4 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
Polymerase|large S protein|
Start
2890
Orient
+
Integrated sequence
AACAACACATAGCGCCTCATTTTGTGGGTCACCATATTCTTGGGAACAAGATCTACAGCATGGGGCAGAATCTTTCCACCAGCAATCCTCTGGGATTCTT| |TCCCGACCACCAGTTGGATCCAGCCTTCAGAGCAAACACCGCAAATCCAGATTGGGACTTCAATCCCAACAAGGACACCTGGCCAGACGCCAACAAGGTA
Host Sequence
Chromosome
chr1
Cytoband
p33
Reference genome
Start
End
50403190/49937518 (Hg38)
Orient
-
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-12136/Upstream/5391966; hsa-mir-101-1/Downstream/1122319;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/1038277, chr1-CpG: 34/Downstream/86227
Upstream sequence
cagacagatcaacgagacagaaagttaacaaggatacccaggaattgaactcagctctgcaccaagcagacctaatagacatctacagaactctccaccc
Downstream sequence
caaatcaacagaatatacatttttttcagcaccacaccacacctattccaaaattgaccacatagttggaagtaaagcactcctcagcaaatgtaaaaga
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.