Basic Information
VIS ID
TVIS10012861
Fusion event
HBV-chr12 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
Polymerase|large S protein|
Start
2885
Orient
+
Integrated sequence
AGAGAAACAACACATAGCGCCTCATTTTGTGGGTCACCATATTCTTGGGAACAAGATCTACAGCATGGGGCAGAATCTTTCCACCAGCAATCCTCTGGGA| |TTCTTTCCCGACCACCAGTTGGATCCAGCCTTCAGAGCAAACACCGCAAATCCAGATTGGGACTTCAATCCCAACAAGGACACCTGGCCAGACGCCAACA
Host Sequence
Chromosome
chr12
Cytoband
p12.3
Reference genome
End
17855652/17702718 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-1244-3/Upstream/29324; hsa-let-7i/Downstream/6509703;
Nearby gene
MIR3974(-29324) ; RERGL(+378151) ;
Upstream sequence
ccttcatttctttatgtacccagtagtcatttaggagcaggttgttcagtttccatgtagttgagcggttttgagtgagattcttaatcctgagttctag
Downstream sequence
ttgattgcactgtggtctgagagacagtttgttataatttctgttcttttacatttgctgaggagtgctttacttccaactatgtggtcaattttgggat
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate