SPATA7 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10012884
Fusion event
HBV-SPATA7 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
Polymerase|large S protein|
Start
2876
Orient
+
Integrated sequence
TTATATAAGAGAGAAACAACACATAGCGCCTCATTTTGTGGGTCACCATATTCTTGGGAACAAGATCTACAGCATGGGGCAGAATCTTTCCACCAGCAAT| |CCTCTGGGATTCTTTCCCGACCACCAGTTGGATCCAGCCTTCAGAGCAAACACCGCAAATCCAGATTGGGACTTCAATCCCAACAAGGACACCTGGCCAG
Host Sequence
Chromosome
chr14
Cytoband
q31.3
Reference genome
GRCh37/hg19
Start
88913359/88447015 (Hg38)
End
88913359/88447015 (Hg38)
Orient
+
Location type
Intronic
Target gene
SPATA7
Nearest miRNA
hsa-mir-1260a/Upstream/11180725; hsa-mir-1185-1/Downstream/5501211;
Nearest TSS
ENST00000550708/Upstream/13858; ENST00000555444/Downstream/22601;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/61074, chr14-CpG: 131/Downstream/31827
Nearby gene
SPATA7(-8555) ; PTPN21(+18763) ;
Upstream sequence
ttttggaataggtgtggtgtggtgctgaaaaaaatgtacattctgttgatttggggtgaagagttctgtagatgtctattatgtctgcttggtgcagagc
Downstream sequence
tgagttcaattcctgggtatccttgttgactttctgtctcgttgatgtgtctaatgttgacagtggggtgttaaagtctcccattattaatgtgtgggag
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate