VISDB Viral Integration Site DataBase

VIS ID

TVIS10012889

Fusion event

HBV-HERC1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|large S protein|

Start

2876

Orient

+

Integrated sequence

TTATATAAGAGAGAAACAACACATAGCGCCTCATTTTGTGGGTCACCATATTCTTGGGAACAAGATCTACAGCATGGGGCAGAATCTTTCCACCAGCAAT| |CCTCTGGGATTCTTTCCCGACCACCAGTTGGATCCAGCCTTCAGAGCAAACACCGCAAATCCAGATTGGGACTTCAATCCCAACAAGGACACCTGGCCAG

Chromosome

chr15

Cytoband

q22.31

Reference genome

Start

End

63912724/63620525 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-455-3p ; hsa-mir-193b-3p ; hsa-mir-324-3p ; hsa-mir-92a-3p ; hsa-mir-18a-5p

Nearest miRNA

hsa-mir-10393/Upstream/796484; hsa-mir-11181/Downstream/250405;

Nearest TSS

Nearest CpG islands

None/Target, chr15-CpG: 55/Upstream/18813, chr15-CpG: 118/Downstream/212790

Upstream sequence

ttttggaataggtgtggtgtggtgctgaaaagaatgtatattctgttgatttggggtggagagttctgtagatatctattaggtctgcttggtgcagagc

Downstream sequence

tgagttcaattcctggatatccttgttaactttctatctcgttgatctgtctaatgttgacagtggggtgttaaagtctcccattattattgtgtgggag