Basic Information
VIS ID
TVIS10012937
Fusion event
HBV-chr4 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
Polymerase|
Start
2509
Orient
+
Integrated sequence
TCGCCGCGTCGCAGAAGATCTCAATCTCGGGAATCTCAATGTTAGTATTCCTTGGACTCATAAGGTGGGGAACTTTACTGGGCTTTATTCTTCTACTGTA| |CCTGTCTTTAATCCTCATTGGAAAACACCATCTTTTCCTAATATACATTTACACCAAGACATTATCAAAAAATGTGAACAGTTTGTAGGCCCACTCACAG
Host Sequence
Chromosome
chr4
Cytoband
q12
Reference genome
End
59148425/58282259 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
Nearest miRNA
hsa-mir-12113/Upstream/5569512; hsa-mir-1243/Downstream/2640360;
Nearby gene
IGFBP7-AS1(-1076960) ;
Upstream sequence
CCTATCAgtgcatatttaggcataggaataaagctggaagggaacacgctaaaatgttaatatcgtttgtctctaaatattgaatttctgggtcatttct
Downstream sequence
caagagatttggaaggggtcaggggcagaatgatatagtttggttgtgtccccacccaaatcccaccttgaattgtattaatctccacttttcaagcgtg
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate