GRID2 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10012943
Fusion event
HBV-GRID2 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
Polymerase|large S protein|
Start
2895
Orient
+
Integrated sequence
CACATAGCGCCTCATTTTGTGGGTCACCATATTCTTGGGAACAAGATCTACAGCATGGGGCAGAATCTTTCCACCAGCAATCCTCTGGGATTCTTTCCCG| |ACCACCAGTTGGATCCAGCCTTCAGAGCAAACACCGCAAATCCAGATTGGGACTTCAATCCCAACAAGGACACCTGGCCAGACGCCAACAAGGTAGGAGC
Host Sequence
Chromosome
chr4
Cytoband
q22.2
Reference genome
GRCh37/hg19
Start
94649535/93728384 (Hg38)
End
94649535/93728384 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA4E
Target gene
GRID2
miRNAs that regulate target gene
hsa-mir-3924 ; hsa-mir-190a-3p ; hsa-mir-5011-5p ; hsa-mir-448
Nearest miRNA
hsa-mir-12113/Upstream/6427801; hsa-mir-1243/Downstream/5269003;
Nearest TSS
ENST00000502981/Upstream/408598; ENST00000637838/Downstream/40846;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/1422528, chr4-CpG: 112/Downstream/99960
Upstream sequence
agagcaccctcatcccttctgccatgggaggacacattgagaagacAGACATCtgtattagtctgttcttatgctgctaataaagaaatacccgagattg
Downstream sequence
tgaggagtgctttacttccaactatgtggtcaattttggaataggtgtggtgtggtgctgaaaaaaatgtatattctgttgatttggggtggagagttct
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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