CHSY3 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10012947
Fusion event
HBV-CHSY3 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
Polymerase|large S protein|
Start
2880
Orient
+
Integrated sequence
ATAAGAGAGAAACAACACATAGCGCCTCATTTTGTGGGTCACCATATTCTTGGGAACAAGATCTACAGCATGGGGCAGAATCTTTCCACCAGCAATCCTC| |TGGGATTCTTTCCCGACCACCAGTTGGATCCAGCCTTCAGAGCAAACACCGCAAATCCAGATTGGGACTTCAATCCCAACAAGGACACCTGGCCAGACGC
Host Sequence
Chromosome
chr5
Cytoband
q23.3
Reference genome
GRCh37/hg19
Start
129421695/130086002 (Hg38)
End
129421695/130086002 (Hg38)
Orient
+
Location type
Intronic
Target gene
CHSY3
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-484
Nearest miRNA
hsa-mir-10397/Upstream/688855; hsa-mir-103a-1/Downstream/2131847;
Nearest TSS
ENST00000502646/Upstream/177915; ENST00000507584/Downstream/1076625;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/180083, chr5-CpG: 27/Downstream/909076
Upstream sequence
tggttttgtttattccttttatttttctcttcactatttgatctctaatcactattatttttttctactaatttttgattttgtctgcttttctttttct
Downstream sequence
atttgctgaggagtgctttacttccaactatgtggtcaattttggaataggtgtggtgtggtgctgaaaaaaatgtatattctgttgatttggggtggag
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate