VISDB Viral Integration Site DataBase

VIS ID

TVIS10012954

Fusion event

HBV-BTNL9 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|Polymerase|

Start

1386

Orient

-

Integrated sequence

GCCGCTTGTTTTGCTCGCAGCAGGTCTGGAGCAAACATTATCGGGACTGATAACTCTGTTGTCCTATCCCGCAAATATACATCGTTTCCATGGCTGCTAG| |GCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTTTACGTCCCGTCGGCGCTGAATCCTGCGGACGACCCTTCTCGGGGTCGCTTGGGACTCTC

Chromosome

chr5

Cytoband

q35.3

Reference genome

Start

End

180477474/181050474 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-192-5p ; hsa-mir-6749-3p ; hsa-mir-6792-3p ; hsa-mir-4691-5p ; hsa-mir-4326 ; hsa-mir-646

Nearest miRNA

hsa-mir-10397/Upstream/6990; hsa-mir-4638/Downstream/172092;

Nearest TSS

Nearest CpG islands

None/Target, chr5-CpG: 87/Upstream/79911, chr5-CpG: 131/Downstream/2111

Upstream sequence

ttttctatgtggaagatatttcacatatctattttaaatctcaacacaacccagcaaggtagtcattaattttcagaaagaaaatggaatcttaaaaaga

Downstream sequence

ATAGGGTGTGTTGGCCTTGACACCTGAAAAGTCAGCACCTTGGATATTAGGAACACACTAAGAACGCTACTGAGAACCCAAACAGTCAGTGAGAGAGGCC