Basic Information
VIS ID
TVIS10012958
Fusion event
HBV-LINC02144 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
Polymerase|large S protein|middle S protein|
Start
3210
Orient
-
Integrated sequence
CGCCAGTCAGGAAGGCAGCCTACCCCGCTGTCTCCACCTTTGAGAAACACTCATCCTCAGGCCATGCAGTGG| |
Host Sequence
Chromosome
chr5
Cytoband
q14.3
Reference genome
GRCh37/hg19
Start
86979911/87684094 (Hg38)
End
86979911/87684094 (Hg38)
Orient
-
Location type
Intronic
Target gene
LINC02144
Nearest miRNA
hsa-mir-10397/Upstream/569140; hsa-mir-103a-1/Downstream/982759;
Nearest TSS
ENST00000502646/Upstream/22052; ENST00000504636/Downstream/49175;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/271033, chr5-CpG: 30/Downstream/457184
Nearby gene
CCNH(-271061) ; TMEM161B(+511112) ;
Upstream sequence
cagagtcttgctctgtcacccaggctggagtgcagtggtgcaatctgtgttcactgcaacctctgcctcccgggttcaagcaattcttctgcctcaacct
Downstream sequence
CTCTCTTTGCTGGAACATCTTTTTCTTTCTTATTTCCCAGGTACGAAGCATCCAGTTTTTAAGATTCAGTCAAGTGTGAAATCCCCTGTGAAGTTTTTAT
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate