Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10012960
Fusion event
HBV-PKIB integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
Polymerase|large S protein|
Start
2882
Orient
+
Integrated sequence
AAGAGAGAAACAACACATAGCGCCTCATTTTGTGGGTCACCATATTCTTGGGAACAAGATCTACAGCATGGGGCAGAATCTTTCCACCAGCAATCCTCTG| |GGATTCTTTCCCGACCACCAGTTGGATCCAGCCTTCAGAGCAAACACCGCAAATCCAGATTGGGACTTCAATCCCAACAAGGACACCTGGCCAGACGCCA
Host Sequence
Chromosome
chr6
Cytoband
q22.31
Reference genome
End
122861858/122540713 (Hg38)
Orient
+
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-10398/Upstream/2525456; hsa-mir-1202/Downstream/3943918;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/68767, chr6-CpG: 50/Downstream/69295
Upstream sequence
gacagtcttgctctgtcacccaggctagagtgcagtggcgtgatctcagatcactgcaacctctgcctcccgggttcaagcaattcttctgcctcaacct
Downstream sequence
gagttcaattcctgggtagtccttgtttacttttgtctcactgatctatctaatgttgacagtgggatgttaaagtctcccattattattgtgtgggagt
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.