LOC646999 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10012966
Fusion event
HBV-LOC646999 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
Polymerase|
Start
2599
Orient
-
Integrated sequence
TTCTACTGTACCTGTCTTTAATCCTCATTGGAAAACACCATCTTTTCCTAATATACATTTACACCAAGACATTATCAAAAAATGTGAACAGTTTGTAGGC| |CCACTCACAGTTAATGAGAAAAGAAGATTGCAATTGATTATGCCTGCCAGGTTTTATCCAAAGGTTACCAAATATTTACCATTGGATAAGGGTATTAAAC
Host Sequence
Chromosome
chr7
Cytoband
p14.1
Reference genome
GRCh37/hg19
Start
39649077/39609478 (Hg38)
End
39649077/39609478 (Hg38)
Orient
+
Location type
upstream
Target gene
LOC646999
Nearest miRNA
hsa-mir-1183/Upstream/2690046; hsa-mir-10399/Downstream/3541417;
Nearest TSS
ENST00000635602/Upstream/39224; ENST00000436179/Downstream/812;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/42701, chr7-CpG: 27/Downstream/176
Upstream sequence
ccttctatggccagcctgcatctaattggttgaactaaggataaaagtggctcagctccctcactccaactcaggacatctggaaggactgtcccagctt
Downstream sequence
ggggtTGTAACAGAGACAAATCTTCGTTATAAGTTTATCAGAAAATGATGATGTTATCGAATTGGGAGAATGGGGAAAGTTGTGGGGACAGTGATAACAG
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate