Basic Information
VIS ID
TVIS10013002
Fusion event
HBV-LINC00534 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
Polymerase|large S protein|
Start
2924
Orient
+
Integrated sequence
TATTCTTGGGAACAAGATCTACAGCATGGGGCAGAATCTTTCCACCAGCAATCCTCTGGGATTCTTTCCCGACCACCAGTTGGATCCAGCCTTCAGAGCA| |AACACCGCAAATCCAGATTGGGACTTCAATCCCAACAAGGACACCTGGCCAGACGCCAACAAGGTAGGAGCTGGAGCATTCGGGCTGGGTTTCACCCCAC
Host Sequence
Chromosome
chr8
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
91278995/90266767 (Hg38)
End
91278995/90266767 (Hg38)
Orient
-
Location type
ncRNA_intronic
Target gene
LINC00534
Nearest miRNA
hsa-mir-12123/Upstream/10025294; hsa-mir-10400/Downstream/938718;
Nearest TSS
ENST00000518652/Upstream/45229; ENST00000519233/Downstream/339298;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/264729, chr8-CpG: 159/Downstream/378394
Upstream sequence
aaaccccaccagaaggaagaaactccgaacacatccgaacatcagaaggaacaaactccggacacgctgcctttaagaactgtaacactcaccgcgaggg
Downstream sequence
caccccaaatcaacagaatatacatttttttcagcaccacaccacacctattccaaaattgaccacatagttggaagtaaagcactcctcagcaaatgta
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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