Basic Information
VIS ID
TVIS10013017
Fusion event
HBV-LINC00630 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
Polymerase|large S protein|
Start
2876
Orient
+
Integrated sequence
TTATATAAGAGAGAAACAACACATAGCGCCTCATTTTGTGGGTCACCATATTCTTGGGAACAAGATCTACAGCATGGGGCAGAATCTTTCCACCAGCAAT| |CCTCTGGGATTCTTTCCCGACCACCAGTTGGATCCAGCCTTCAGAGCAAACACCGCAAATCCAGATTGGGACTTCAATCCCAACAAGGACACCTGGCCAG
Host Sequence
Chromosome
chrX
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
102129507/102874579 (Hg38)
End
102129507/102874579 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
LINC00630
Nearest miRNA
hsa-let-7f-2/Upstream/7811353; hsa-mir-105-1/Downstream/3765235;
Nearest TSS
ENST00000429181/Upstream/34671; ENST00000429932/Downstream/9835;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/105252, chrX-CpG: 28/Downstream/62678
Upstream sequence
aactggattctttcaataacatgaatcagcttggaagacgattcatccccaaaatctattgataagagtctggctagggcaacaccttaagtatgagatc
Downstream sequence
tgaggagtgctttacttccaactatgtggtcaattttggaataggtgtggtgtggtgctgaaaaaaatgtatattctgttgatttggggtggagagttct
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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