UPRT _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10013027
Fusion event
HBV-UPRT integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
Polymerase|large S protein|
Start
2880
Orient
+
Integrated sequence
ATAAGAGAGAAACAACACATAGCGCCTCATTTTGTGGGTCACCATATTCTTGGGAACAAGATCTACAGCATGGGGCAGAATCTTTCCACCAGCAATCCTC| |TGGGATTCTTTCCCGACCACCAGTTGGATCCAGCCTTCAGAGCAAACACCGCAAATCCAGATTGGGACTTCAATCCCAACAAGGACACCTGGCCAGACGC
Host Sequence
Chromosome
chrX
Cytoband
q13.3
Reference genome
GRCh37/hg19
Start
74469615/75249780 (Hg38)
End
74469615/75249780 (Hg38)
Orient
-
Location type
Intronic
Target gene
UPRT
Nearest miRNA
hsa-let-7f-2/Upstream/962423; hsa-mir-105-1/Downstream/1669493;
Nearest TSS
ENST00000429181/Upstream/93048; ENST00000373373/Downstream/24305;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/324471, chrX-CpG: 31/Downstream/273150
Nearby gene
ABCB7(-93483) ; UPRT(+24279) ;
Upstream sequence
gttagggttagggttagggttagggttagggttagggttagggttagggttagggttagggttagggttagggttagggttagggttagggttagggtga
Downstream sequence
ctattccaaaattgaccacatagttggaagtaaagcactcctcagcaaatgtaaaagaacagaaattataacaaactgtctctcagaccacagtgcaatc
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate