VISDB Viral Integration Site DataBase

VIS ID

TVIS10013031

Fusion event

HBV-AURKAIP1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|

Start

2713

Orient

+

Integrated sequence

TGAGAAAAGAAGATTGCAATTGATTATGCCTGCCAGGTTTTATCCAAAGGTTACCAAATATTTACCATTGGATAAGGGTATTAAACCTTATTATCCAGAA| |CATCTAGTTAATCATTACTTCCAAACTAGACACTATTTACACACTCTATGGAAGGCGGGTATATTATATAAGAGAGAAACAACACATAGCGCCTCATTTT

Chromosome

chr1

Cytoband

p36.33

Reference genome

Start

End

1309836/1374456 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-331-3p ; hsa-mir-26a-5p ; hsa-mir-218-5p ; hsa-mir-15a-5p ; hsa-mir-15b-5p ; hsa-mir-16-5p ; hsa-mir-195-5p ; hsa-mir-424-5p ; hsa-mir-497-5p ; hsa-mir-6838-5p

Nearest miRNA

hsa-mir-12136/Upstream/34748; hsa-mir-101-1/Downstream/1753519;

Nearest TSS

Nearest CpG islands

chr1-CpG: 158/Target, None/Upstream, None/Downstream

Upstream sequence

CCTACCTGGGCCGGCCGGCGATGTGCTGTAAAGGGGCCCGCAGACCCGGCTGCCCAGCACTCCAGAGACGGGCCAAGGCGGGCGGCCGCCTGCAGAAAAC

Downstream sequence

CAGACGCCACGGTCACCGCTCGCGAGACCACACAGGCCCGTCGGGTTGAGGAGCAGCAGGTTCGTCCCAGCGAGGATCCCCCGCACCTCATTCCTGGCCT