VISDB Viral Integration Site DataBase

VIS ID

TVIS10013045

Fusion event

HBV-GPR158 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1786

Orient

-

Integrated sequence

AACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGT| |AGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCT

Chromosome

chr10

Cytoband

p12.1

Reference genome

Start

End

25569663/25280734 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-374b-5p ; hsa-mir-374a-5p ; hsa-mir-4666a-5p ; hsa-mir-4772-3p ; hsa-mir-4699-3p ; hsa-mir-944 ; hsa-mir-629-3p ; hsa-mir-374a-3p ; hsa-mir-136-5p ; hsa-mir-1266-3p ; hsa-mir-519e-5p ; hsa-mir-515-5p

Nearest miRNA

hsa-mir-1265/Upstream/1004953; hsa-mir-107/Downstream/3008524;

Nearest TSS

Nearest CpG islands

None/Target, chr10-CpG: 68/Upstream/104024, chr10-CpG: 96/Downstream/653258

Upstream sequence

acagactgcatttttttctcaaaacattcataaaagttgaccatgaagccataaatcacatatcaacacattttatgtatgtatgtatgtatgtatgtat

Downstream sequence

gtatgtacgtacgtacatacgtacatattcttttaccaagaaacgaatctgaatcaacacattttaaagagctagtatactgaccacatgctgtgcctct