Fusion event
HBV-SORL1 integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Region type
S protein|Polymerase|large S protein|middle S protein|
Integrated sequence
TCACAATACCGCAGAGTCTAGACTCGTGGTGGACTTCTCTCAATTTTCTAGGGGGAACTACCGTGTGTCTTGGCCAAAATTCGCAGTCCCCAACCTCCAA| |TCACTCACCAACCTCTTGTCCTCCAACTTGTCCTGGTTATCGCTGGATGTGTCTGCGGCGTTTTATCATCTTCCTCTTCATCCTGCTGCTATGCCTCATC
End
121439970/121569261 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-10392/Upstream/2256249; hsa-let-7a-2/Downstream/530496;
Upstream sequence
tatgcctgtctttactttaatctcttaatcccgtcatcttcgtaagctgaggaggatgtatgtcgcctcaggaccctgtgatgattgcattaactgcaca
Downstream sequence
aattgtagagcatgtgtgtttgaacaatatgaaatctgggcaccttgaaaaaagaacaggataacagcaatgttcagggaacaagacagataaccttaaa
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.