VISDB Viral Integration Site DataBase

VIS ID

TVIS10013057

Fusion event

HBV-C12orf60 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

S protein|Polymerase|large S protein|middle S protein|

Start

332

Orient

+

Integrated sequence

TCACAATACCGCAGAGTCTAGACTCGTGGTGGACTTCTCTCAATTTTCTAGGGGGAACTACCGTGTGTCTTGGCCAAAATTCGCAGTCCCCAACCTCCAA| |TCACTCACCAACCTCTTGTCCTCCAACTTGTCCTGGTTATCGCTGGATGTGTCTGCGGCGTTTTATCATCTTCCTCTTCATCCTGCTGCTATGCCTCATC

Chromosome

chr12

Cytoband

p12.3

Reference genome

Start

End

14899348/14746414 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-574-5p ; hsa-mir-297 ; hsa-mir-6867-5p ; hsa-mir-567 ; hsa-mir-223-5p ; hsa-mir-511-3p ; hsa-mir-5579-5p

Nearest miRNA

hsa-mir-1244-3/Upstream/1830496; hsa-let-7i/Downstream/2926885;

Nearest TSS

Nearest CpG islands

None/Target, chr12-CpG: 104/Upstream/178255, chr12-CpG: 86/Downstream/23529

Nearby gene

GUCY2C(-49829) ; HIST4H4(+24306) ;

Upstream sequence

taaggttatctctcttgttccctgaacattgctgttatcctgttcttttttcaaggtgcccagatttcatattgttcaaacacacatgctctaaaatttg

Downstream sequence

tgcagttaatgcaatcatcacagggtcctgaggcgacatacatcctcctcagtttacgagatgacaggattaagagattaaagtaaagacaggcatagga