VISDB Viral Integration Site DataBase

VIS ID

TVIS10013060

Fusion event

HBV-ERGIC2 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

S protein|Polymerase|large S protein|middle S protein|

Start

552

Orient

+

Integrated sequence

CTATCAAGGTATGTTGCCCGTTTGTCCTCTAATTCCAGGATCCTCAACAACCAGCACGGGACCATGCCGGACCTGCATGACTACTGCTCAAGGAACCTCT| |ATGTATCCCTCCTGTTGCTGTACCAAACCTTCGGACGGAAATTGCACCTGTATTCCCATCCCATCATCCTGGGCTTTCGGAAAATTCCTATGGGAGTGGG

Chromosome

chr12

Cytoband

p11.22

Reference genome

Start

End

29534211/29381278 (Hg38)

Orient

-

Location type

upstream

Target gene

miRNAs that regulate target gene

hsa-mir-98-5p ; hsa-mir-32-5p ; hsa-let-7b-5p ; hsa-mir-671-3p ; hsa-mir-92a-3p ; hsa-mir-1277-5p ; hsa-mir-6079 ; hsa-mir-1273e ; hsa-mir-6894-5p ; hsa-mir-671-5p ; hsa-mir-6828-5p ; hsa-mir-4722-5p ; hsa-mir-151b ; hsa-mir-151a-5p ; hsa-mir-3131 ; hsa-mir-611 ; hsa-mir-6840-3p ; hsa-mir-665 ; hsa-mir-4433a-3p ; hsa-mir-4459 ; hsa-mir-6165 ; hsa-mir-448 ; hsa-mir-153-3p ; hsa-mir-6800-5p ; hsa-mir-6739-5p ; hsa-mir-6733-5p ; hsa-mir-3153 ; hsa-mir-135a-3p ; hsa-mir-9500 ; hsa-mir-6822-5p ; hsa-mir-5584-5p ; hsa-mir-6750-5p ; hsa-mir-495-5p ; hsa-mir-520e ; hsa-mir-520d-3p ; hsa-mir-520c-3p ; hsa-mir-520b ; hsa-mir-520a-3p ; hsa-mir-373-3p ; hsa-mir-372-3p ; hsa-mir-302e ; hsa-mir-302d-3p ; hsa-mir-302c-3p ; hsa-mir-302b-3p ; hsa-mir-302a-3p ; hsa-mir-4796-3p ; hsa-mir-93-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-106a-5p ; hsa-mir-3609 ; hsa-mir-548ah-5p ; hsa-mir-3613-3p ; hsa-mir-561-3p ; hsa-mir-5687 ; hsa-mir-4699-5p ; hsa-mir-500a-5p ; hsa-mir-3121-3p ; hsa-mir-5585-3p ; hsa-mir-6844 ; hsa-mir-4795-3p ; hsa-mir-4477a ; hsa-mir-627-3p ; hsa-mir-195-3p ; hsa-mir-16-2-3p ; hsa-mir-126-5p ; hsa-mir-338-5p ; hsa-mir-25-3p ; hsa-mir-363-3p ; hsa-mir-367-3p ; hsa-mir-92b-3p ; hsa-mir-4778-3p ; hsa-mir-5009-3p ; hsa-mir-761 ; hsa-mir-3619-5p ; hsa-mir-214-3p ; hsa-mir-6510-5p ; hsa-mir-944 ; hsa-mir-4518 ; hsa-mir-1266-5p ; hsa-mir-3664-3p ; hsa-mir-654-3p ; hsa-mir-329-5p ; hsa-mir-4446-5p ; hsa-mir-4307 ; hsa-mir-576-3p ; hsa-mir-33a-3p ; hsa-mir-6839-3p ; hsa-mir-4507 ; hsa-mir-3940-5p ; hsa-mir-6740-5p ; hsa-mir-629-5p ; hsa-mir-500b-5p ; hsa-mir-362-5p

Nearest miRNA

hsa-mir-1244-3/Upstream/3507199; hsa-let-7i/Downstream/12942422;

Nearest TSS

Nearest CpG islands

chr12-CpG: 20/Target, None/Upstream, None/Downstream

Upstream sequence

TACCCGGAAATATCGCGAGAACAAAAGCGACTATCACAGCTGAAAACGTCAGAAAAGAGACAATGTACAGATCTCGCGATATTCCCTTTGCTTACGACGT

Downstream sequence

GCTTAGGGAATGAAGAGGCGTGGTTAAGATAAAAGAGGCGTGCCTACAGGGAAATGAGGTTGCAACTTGTTTTAGGTGTAATCGCGCCGCCAGTCCGGTT