Basic Information
VIS ID
TVIS10013068
Fusion event
HBV-chr17 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
Polymerase|
Start
987
Orient
-
Integrated sequence
GTCATTGGATGTTATGGGTCCTTGCCACAAGAACACATCATACAAAAAATCAAAGAATGTTTTAGAAAACTTCCTATTAACAGGCCTATTGATTGGAAAG| |TATGTCAACGAATTGTGGGTCTTTTGGGTTTTGCTGCCCCTTTTACACAATGTGGTTATCCTGCGTTGATGCCTTTGTATGCATGTATTCAATCTAAGCA
Host Sequence
Chromosome
chr17
Cytoband
q25.3
Reference genome
GRCh37/hg19
Start
81194952/83247183 (Hg38)
End
81194952/83247183 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-10226/Upstream/578876;
Nearest TSS
ENST00000595228/Upstream/19462;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/29703, None/Downstream
Nearby gene
RPL23AP87(-6379) ;
Upstream sequence
aaggatgattttgagtgattatttgtgtaagttgtaaagttttcatctacatgtgagggtgagggtgagggtgagggttaggggttaggggttaggggtt
Downstream sequence
agggctagggctagggctagggctagggctagggctagggtttagggttagggttagggttagggttagggttagggttaggttagggtgagggtgaggg
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate