VISDB Viral Integration Site DataBase

VIS ID

TVIS10013070

Fusion event

HBV-ANKRD29 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|precore/core protein|

Start

1827

Orient

-

Integrated sequence

AAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTT| |CACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAAT

Chromosome

chr18

Cytoband

q11.2

Reference genome

Start

End

21243228/23663264 (Hg38)

Orient

+

Location type

upstream

Target gene

miRNAs that regulate target gene

hsa-mir-1-3p ; hsa-mir-335-5p ; hsa-mir-340-5p ; hsa-mir-130b-3p ; hsa-mir-132-3p ; hsa-mir-93-5p ; hsa-mir-33a-5p

Nearest miRNA

hsa-mir-1-2/Upstream/729826; hsa-mir-122/Downstream/658411;

Nearest TSS

Nearest CpG islands

None/Target, chr18-CpG: 67/Upstream/254, chr18-CpG: 118/Downstream/26041

Upstream sequence

actcacacacaaactccatacataTCCTCCCAAATAGACTGGTCTGCCCCAGAGGACTCCCAACCTTCATTACAGCACAAATATTATAATGATGTAAAAA

Downstream sequence

TGAAGCTTGAGGAAAAAATTCATCCAATAGCTATTTTCGTTATAATTTCTTTCTCGGTTTCCTGGGAAACTTTTTTCTCCTGGGGAAAATATCTAGGAAA