VISDB Viral Integration Site DataBase

VIS ID

TVIS10013073

Fusion event

HBV-NCKAP5 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|Polymerase|

Start

2424

Orient

+

Integrated sequence

AACACTTCCGGAGACTACTGTTGTTAGACGACGAGGCAGGTCCCCTAGAAGAAGAACTCCCTCGCCTCGCAGACGAAGGTCTCAATCGCCGCGTCGCAGA| |AGATCTCAATCTCGGGAATCTCAATGTTAGTATTCCTTGGACTCATAAGGTGGGGAACTTTACTGGGCTTTATTCTTCTACTGTACCTGTCTTTAATCCT

Chromosome

chr2

Cytoband

q21.2

Reference genome

Start

End

133576309/132818736 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-130b-3p ; hsa-mir-19b-3p ; hsa-mir-7977 ; hsa-mir-6892-5p ; hsa-mir-3925-3p ; hsa-mir-4267 ; hsa-mir-5588-3p ; hsa-mir-4475 ; hsa-mir-518e-3p

Nearest miRNA

hsa-mir-1285-2/Upstream/384916; hsa-mir-10b/Downstream/1308389;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/147439, chr2-CpG: 52/Downstream/447639

Upstream sequence

gagattgtgccactgcactccagcctgggtgacagagtgtgacctagaattcaagatatttataaatttggatggaaaaaaaatgcatctttagtttcat

Downstream sequence

taaacttgaaccaaaattcagtatttccttcagttatgaatggaggcatcaaactacagtgctataaacttgtgactttgtctccaacagaaattacaga