VISDB Viral Integration Site DataBase

VIS ID

TVIS10013076

Fusion event

HBV-ICA1L integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|

Start

2767

Orient

-

Integrated sequence

CAAATATTTACCATTGGATAAGGGTATTAAACCTTATTATCCAGAACATCTAGTTAATCATTACTTCCAAACTAGACACTATTTACACACTCTATGGAAG| |GCGGGTATATTATATAAGAGAGAAACAACACATAGCGCCTCATTTTGTGGGTCACCATATTCTTGGGAACAAGATCTACAGCATGGGGCAGAATCTTTCC

Chromosome

chr2

Cytoband

q33.2

Reference genome

Start

End

203675634/202810911 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-218-5p ; hsa-mir-1303 ; hsa-mir-5096 ; hsa-mir-6848-3p ; hsa-mir-6843-3p ; hsa-mir-378a-5p ; hsa-mir-197-3p ; hsa-mir-4662a-5p ; hsa-mir-193b-5p ; hsa-mir-1193 ; hsa-mir-1976 ; hsa-mir-136-5p ; hsa-mir-4716-5p ; hsa-mir-2392 ; hsa-mir-575 ; hsa-mir-4676-5p ; hsa-mir-3149 ; hsa-mir-452-3p ; hsa-mir-589-3p ; hsa-mir-6878-3p ; hsa-mir-190a-3p ; hsa-mir-6744-3p ; hsa-mir-4312 ; hsa-mir-4757-5p ; hsa-mir-150-5p ; hsa-mir-212-5p ; hsa-mir-186-3p ; hsa-mir-520h ; hsa-mir-1295b-3p ; hsa-mir-520g-3p ; hsa-mir-512-3p ; hsa-mir-520e ; hsa-mir-520d-3p ; hsa-mir-520c-3p ; hsa-mir-520b ; hsa-mir-520a-3p ; hsa-mir-373-3p ; hsa-mir-372-3p ; hsa-mir-302e ; hsa-mir-302d-3p ; hsa-mir-302c-3p ; hsa-mir-302b-3p ; hsa-mir-302a-3p ; hsa-mir-93-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-106a-5p ; hsa-mir-566 ; hsa-mir-6789-3p ; hsa-mir-2276-3p ; hsa-mir-6787-3p ; hsa-mir-1304-3p ; hsa-mir-4485-5p ; hsa-mir-6736-3p ; hsa-mir-6890-3p ; hsa-mir-5089-5p ; hsa-mir-4715-3p ; hsa-mir-4727-5p ; hsa-mir-7151-3p ; hsa-mir-5095 ; hsa-mir-6778-3p ; hsa-mir-6506-5p ; hsa-mir-619-5p ; hsa-mir-6817-5p ; hsa-mir-4769-3p ; hsa-mir-6747-3p ; hsa-mir-6727-3p ; hsa-mir-4722-3p ; hsa-mir-6814-5p ; hsa-mir-5697 ; hsa-mir-6504-3p ; hsa-mir-4438 ; hsa-mir-562 ; hsa-mir-365b-5p ; hsa-mir-365a-5p ; hsa-mir-8052 ; hsa-mir-3199 ; hsa-mir-1203 ; hsa-mir-6894-3p ; hsa-mir-4763-5p

Nearest miRNA

hsa-mir-10b/Upstream/13677800; hsa-mir-1244-1/Downstream/3972323;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/36477, chr2-CpG: 106/Downstream/60291

Upstream sequence

gggggcagctgtcttttatggtcatagctgtgggatgaaataagccctggtctcctgtagcgctcccaggcttattaggacgaggaaattcccgcttaat

Downstream sequence

aaattttggtcagaccagttgtctgctctcaaaccgtgtctctgataagatgttatcaatgacaatgcctgcccgaaacttcattagcaattttaacttc