Basic Information
VIS ID
TVIS10013082
Fusion event
HBV-IGK integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
S protein|Polymerase|large S protein|middle S protein|
Start
778
Orient
-
Integrated sequence
TTACTAGTGCCATTTGTTCAGTGGTTCGTAGGGCTTTCCCCCACTGTTTGGCTTTCAGTTATATGGATGATGTGGTATTGGGGGCCAAGTCTGTACAGCA| |TCTTGAGTCCCTTTTTACCGCTGTTACCAATTTTCTTTTGTCTTTGGGTATACATTTAAACCCTAACAAAACAAAGAGATGGGGTTACTCTCTAAATTTT
Host Sequence
Chromosome
chr2
Cytoband
p11.2
Reference genome
End
89867410/89828600 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
Target gene
Nearest miRNA
hsa-mir-1285-2/Upstream/1016146; hsa-mir-10b/Downstream/6969678;
Nearby gene
MIR4436A(-755442) ; LSP1P4(+1957299) ;
Upstream sequence
ttccattccattccactgcattccattccattccattccactcgggttgattccatcccattccattcagttgcattgcattccattccattccattcca
Downstream sequence
gttgattccattccattccattccattccattccattccattccattccattccactaggtttgattccattccattccattccattccattccattcca
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate