VISDB Viral Integration Site DataBase

VIS ID

TVIS10013112

Fusion event

HBV-PTCD2 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

S protein|Polymerase|large S protein|middle S protein|

Start

332

Orient

+

Integrated sequence

TCACAATACCGCAGAGTCTAGACTCGTGGTGGACTTCTCTCAATTTTCTAGGGGGAACTACCGTGTGTCTTGGCCAAAATTCGCAGTCCCCAACCTCCAA| |TCACTCACCAACCTCTTGTCCTCCAACTTGTCCTGGTTATCGCTGGATGTGTCTGCGGCGTTTTATCATCTTCCTCTTCATCCTGCTGCTATGCCTCATC

Chromosome

chr5

Cytoband

q13.2

Reference genome

Start

End

71641230/72345403 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-423-3p ; hsa-mir-129-5p ; hsa-mir-3680-3p ; hsa-mir-557 ; hsa-mir-507 ; hsa-mir-450b-5p ; hsa-mir-4531 ; hsa-mir-4666b ; hsa-mir-5011-3p ; hsa-mir-19b-3p ; hsa-mir-19a-3p ; hsa-mir-5703 ; hsa-mir-4516 ; hsa-mir-4434 ; hsa-mir-539-5p ; hsa-mir-199b-5p ; hsa-mir-199a-5p ; hsa-mir-3613-3p ; hsa-mir-575 ; hsa-mir-4676-5p ; hsa-mir-1827 ; hsa-mir-1910-3p ; hsa-mir-298 ; hsa-mir-3160-3p ; hsa-mir-3190-5p ; hsa-mir-3612 ; hsa-mir-3675-3p ; hsa-mir-3926 ; hsa-mir-4459 ; hsa-mir-4487 ; hsa-mir-455-3p ; hsa-mir-4684-5p ; hsa-mir-4695-5p ; hsa-mir-495-5p ; hsa-mir-548s ; hsa-mir-558 ; hsa-mir-6499-3p ; hsa-mir-650 ; hsa-mir-6511a-5p ; hsa-mir-6516-5p ; hsa-mir-665 ; hsa-mir-6771-3p ; hsa-mir-6840-3p ; hsa-mir-6849-3p

Nearest miRNA

hsa-mir-10397/Upstream/175863; hsa-mir-103a-1/Downstream/533188;

Nearest TSS

Nearest CpG islands

None/Target, chr5-CpG: 87/Upstream/24885, chr5-CpG: 47/Downstream/72037

Upstream sequence

catcagagaagctaggactacaggcatgcaccaccatggggggctaattttttaattttttgtagagacgggatcttgctatgtttcccagactggtctc

Downstream sequence

tgcagttaatgcaatcatcacagggtcctgaggcgacatacatcctcctcagtttaagaagatgacgggattaagagattaaagacaggcataggaaatc