VISDB Viral Integration Site DataBase

VIS ID

TVIS10013123

Fusion event

HBV-SKAP2 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|

Start

2746

Orient

+

Integrated sequence

CAGGTTTTATCCAAAGGTTACCAAATATTTACCATTGGATAAGGGTATTAAACCTTATTATCCAGAACATCTAGTTAATCATTACTTCCAAACTAGACAC| |TATTTACACACTCTATGGAAGGCGGGTATATTATATAAGAGAGAAACAACACATAGCGCCTCATTTTGTGGGTCACCATATTCTTGGGAACAAGATCTAC

Chromosome

chr7

Cytoband

p15.2

Reference genome

Start

End

26720462/26680843 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-15a-5p ; hsa-mir-16-5p ; hsa-mir-335-5p ; hsa-mir-484 ; hsa-mir-498 ; hsa-mir-5001-3p ; hsa-mir-24-2-5p ; hsa-mir-24-1-5p ; hsa-mir-6813-3p ; hsa-mir-3200-3p ; hsa-mir-5571-5p ; hsa-mir-4762-3p ; hsa-mir-4309 ; hsa-mir-3198 ; hsa-mir-4303 ; hsa-mir-6794-3p ; hsa-mir-4294 ; hsa-mir-1289 ; hsa-mir-8082 ; hsa-mir-4534 ; hsa-mir-1273f ; hsa-mir-4708-5p ; hsa-mir-6088 ; hsa-mir-4770 ; hsa-mir-6761-5p ; hsa-mir-143-3p ; hsa-mir-4329 ; hsa-mir-4251 ; hsa-mir-1304-3p ; hsa-mir-4639-3p ; hsa-mir-6514-5p ; hsa-mir-3664-5p ; hsa-mir-4652-3p ; hsa-mir-4778-5p ; hsa-mir-5186

Nearest miRNA

hsa-mir-1183/Upstream/730857; hsa-mir-10399/Downstream/488637;

Nearest TSS

Nearest CpG islands

None/Target, chr7-CpG: 39/Upstream/281748, chr7-CpG: 64/Downstream/183407

Upstream sequence

ccacctcggcctctcaaagtgctgggattacaggtgtgagccatcgtgccctgccTAGCttttgtatttttagtagagatggggtttcgccatgttgggc

Downstream sequence

GAAAATGTTAAAAAGGGAAGGAGGAAGGGCACAGTATCTGCCTACTCTTCTTTCTTTATTGCAACATTTGATTTGCACCAGAAGAAAAAAAAAAATAAAG