VISDB Viral Integration Site DataBase

VIS ID

TVIS10013128

Fusion event

HBV-ZFHX4 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|

Start

2473

Orient

-

Integrated sequence

AGAAGAACTCCCTCGCCTCGCAGACGAAGGTCTCAATCGCCGCGTCGCAGAAGATCTCAATCTCGGGAATCTCAATGTTAGTATTCCTTGGACTCATAAG| |GTGGGGAACTTTACTGGGCTTTATTCTTCTACTGTACCTGTCTTTAATCCTCATTGGAAAACACCATCTTTTCCTAATATACATTTACACCAAGACATTA

Chromosome

chr8

Cytoband

q21.13

Reference genome

Start

End

77664707/76752471 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-296-3p ; hsa-mir-128-3p ; hsa-mir-183-5p ; hsa-mir-92a-3p ; hsa-mir-19b-3p ; hsa-let-7b-5p ; hsa-mir-15a-5p ; hsa-mir-16-5p ; hsa-mir-200b-3p ; hsa-mir-15b-5p ; hsa-mir-195-5p ; hsa-mir-200c-3p ; hsa-mir-369-3p ; hsa-mir-424-5p ; hsa-mir-429 ; hsa-mir-409-3p ; hsa-mir-497-5p ; hsa-mir-545-3p ; hsa-mir-4524a-5p ; hsa-mir-4524b-5p ; hsa-mir-6838-5p ; hsa-mir-8084 ; hsa-mir-599 ; hsa-mir-3161 ; hsa-mir-5003-3p ; hsa-mir-646 ; hsa-mir-503-5p

Nearest miRNA

hsa-mir-124-1/Upstream/2046724; hsa-mir-10400/Downstream/214297;

Nearest TSS

Nearest CpG islands

None/Target, chr8-CpG: 109/Upstream/69846, chr8-CpG: 78/Downstream/247425

Upstream sequence

aaccccaaccccaaccctaaacccaaccccaaccccaacccgaccctgaccccgacccctaaccctaaaccctaacccctaaccctaaccctacccctag

Downstream sequence

tctctaccaaaaatccaaaaaaaaaaaaaaaaaaaaaagaaaaaagaactttagctgggcatggtggcacatgcctgtaatctcagctactaggaaagct